About LeGene Biosciences

LeGene Biosciences is a San Diego-based biotechnology company specializing in enzyme research, development and manufacturing. We produce kits and reagents for diverse life science and drug discovery applications worldwide. Our mission is to create quality products that consistently deliver high performance, to discover innovative technological solutions that lead to better results, and to develop collaborative relationships with our clients through personalized attention and follow-through. With our commitment to excellence and our pioneering spirit, we offer exceptional product at great value and bring leading-edge technology to the market.

Leaders in Innovation

Founding members of LeGene Biosciences have extensive expertise in enzyme research and have played leading roles in the development of cutting-edge technologies such as Invitrogen’s SuperScript^®III RT, ThermoScript^® RT, Pfx50^TM DNA polymerase, and AccuPrime^TM Taq DNA polymerase.

Led by our commitment to excellence and our pioneering spirit, we offer exceptional product at great value and bring leading-edge technology to the market. LeGene Biosciences played a leading role in the development of innovative “One-Tube Master Mix” products such as Multi-Probe qPCR Master Mix, ViralPath RT-qPCR Master Mixes, cDNA Synthesis Master Mixes and RT-PCR Super Mixes. A strong foundation in scientific research, history of innovative product development, and dedication to exploration and discovery make LeGene Biosciences the ideal partner for bringing pioneering technology to the market for laboratory research worldwide.

Current Events - Publications

Using single nuclei for RNA-Seq to capture the transcriptome of postmortem neurons

Nature Protocols, Vol.11, No3, p499-524 (2016): Rashel V. Grindberg, Suguna Rani, Krishnaswami, Mark Novotny, Pratap Venepally, Benjamin Lacar, Kunal Bhutani, Sara B. Linker Son Pham, Jennifer A. Erwin, Jeremy A. Miller, Rebecca Hodge, James K. McCarthy, Martijn Kelder, Jamison McCorrison, Brian D. Aevermann, Francisco Diez Fuertes Richard H. Scheuermann, Jun Lee, Ed S. Lein, Nicholas Schork, Michael J. McConnell, Fred H. Gage , Roger S. Lasken.

RNA-Seq from Single Nuclei

PNAS, 110 (49) 19802-19807 (2013): Rashel V. Grindberg, Joyclyn L. Yee-Greenbaum, Michael J. McConnell, Mark Novotny, Andy L. O’ Shaughnessy, Georgina M. Lambert, Marcos J. Araúzo-Bravo, Jun Lee, Max Fishman, Gillian E. Robbins, Xiaoying Lin, Pratap Venepally, Jonathan H. Badger, David W. Galbraith, Fred H. Gage, Roger S. Lasken.